Jessica R. Craig，Frank R. Dunshea，Jeremy J. Cottrell，John B. Furness，Udani A. Wijesiriwardana，John R. Pluske
翻译&校对：上海亘泰实业集团
与经产母猪子代（SP）相比，从出生开始，后备母猪子代（GP）的生长性能和健康状况表现往往受到一定程度的限制，其潜在机制尚不完全清楚。本研究旨在比较GP和SP在出生后前24h和断奶前后生长发育的差异。
试验选择36头GP和37头SP，分别在4个时间点进行安乐死： ①出生组：出生后哺乳前，出生0h、出生24h后，n=33； ②断奶组：29d左右，断奶前（PrW）、断奶后24h（PoW），n=40。安乐死之前，分别在出生后0 h、24 h、PrW和PoW时对仔猪进行称重，记录所选组织、器官相对于体重（BW）的重量，并进行分析；同时测量小肠 （SI）、股骨和身体长度；收集血清样本，分析IgG浓度。收集空肠和回肠粘膜样品，分析总蛋白和乳糖酶的比活度。
试验数据表明，与SP比较：GP组，各时间点实施安乐死的BW都较轻（P < 0.01）；各时间点，GP组股四头肌重量与股骨长、BW与体长、脾脏重量与BW比值均显著降低（P < 0.05）、SI重量与长度比值相对较低 （P < 0.10）；胃和心脏与BW的比值没有显著差异 （P ≥ 0.05）。在出生组中，与SP比较，GP猪只脑与肝脏重量比值显著增加（P = 0.044），肝脏与BW比值相似（P = 0.35）；在断奶组中，GP肝脏与BW比值显著升高（P = 0.014）。在出生和断奶两个组中，GP的脑与BW比值均极显著升高（P < 0.01）。在出生24h时，GP空肠和回肠粘膜总蛋白含量极显著下降（P = 0.007）；血清IgG浓度也极显著降低（P < 0.001），但在断奶阶段没有显著变化（P ≥ 0.10）。在出生组中，GP的乳糖酶比活度显著升高（P = 0.022），而断奶组中无差异（P ≥ 0.10）。
综上所述，这些研究结果表明，与SP相比，GP的早期发育可能会被延迟， 而且GP和SP之间在出生后存在的一些解剖学差异到断奶时也仍然存在。
A comparison of the anatomical and gastrointestinal functional development between gilt and sow progeny around birth and weaning
Gilt progeny (GP) often have restricted growth performance and health status in comparison to sow progeny (SP) from birth, with the underlying mechanisms responsible for this yet to be fully understood. The present study aimed to compare differences in growth and development between GP and SP in the first 24 h after birth and in the periweaning period. Two cohorts of pigs including 36 GP and 37 SP were euthanized at 1 of 4 time points: a birth cohort (at birth before suckling, 0 h; and 24 h after birth, 24 h; n = 33) and a weaning cohort (at approximately 29 d of age; “pre-weaning,” PrW; and 24 h after weaning; “post-weaning,” PoW; n = 40). Pigs were individually weighed at 0 h, 24 h, PrW, and PoW up until the point of euthanasia, at which time the weights of selected tissues and organs were recorded and analyzed relative to BW. The length of the small intestine (SI), femur, and body were also measured, and a serum sample was collected and analyzed for IgG concentration.（转自：猪营养国际论坛）